Category Archives: Healthcare IT

Insulin Resistance Market Outlook to 2024 Latest Industry Forecast Report

Insulin Resistance Market: Overview

Diabetes has become a major concern across the globe owing to its increasing prevalence. Statistics published by World Health Organization (WHO) suggests that over 350 million individuals suffer from diabetes globally. The data also details that more that 80% cases are recorded in low and middle income countries, majority of which are from Asia Pacific, the Middle East and African countries. India accounts for maximum cases of diabetes with more than 30 million cases registered in year 2000. According to Medscape, a healthcare website, in the United States, the prevalence of insulin resistance is over 3%.

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Insulin resistance is a complication in which body develops resistance to insulin due to its over production. As the sensitivity towards insulin decreases, body produces excess insulin for better absorption of glucose. This conditions leads to development of type 2 diabetes or prediabetes. Prediabetes is a condition in which blood glucose level is higher than the normal level, but not enough for proper diagnosis of diabetes. Although exact cause of insulin resistance is not known, scientists and doctor believe that excess and sedentary lifestyle are main causes for development of the disorder. Major symptoms of insulin resistance are lethargy, hunger, high blood pressure, atherosclerosis, and kidney damage. Insulin resistance diagnosis is difficult and involves combination of tests. Usually hyperinsulinemic euglycemic clamp test is used to measures the amount of glucose which is necessary to compensate for increased insulin level without causing hypoglycemia. Other tests include glucose tolerance test and fasting insulin level.

Insulin Resistance Market: Drivers and Restraints

Few drugs approved by FDA are available in the market for treatment of insulin resistance. Humulin by Lilly LLC, and Novolin and Velosulin by Novo Nordisk, are the major brands in the market. Various off label drugs are also prescribed to suppress the symptoms of insulin resistance. Inadequate clinical information on insulin resistance has restricted the scope of drug development. Although scientists are trying to gain insight for exact cause of insulin resistance, development of drugs may take more time owing to lengthy clinical trials. Diabetes and the consequent insulin resistance being a major concern in most of the countries, government initiatives to motivate research in diabetes is expected to give rise to more research projects for diabetes and insulin resistance. Aging population and increasing obesity prevalence in developing countries is expected to give rise to patients suffering from insulin resistance. According to Centers for Disease Control and Prevention (CDC), more than 35% of the U.S. population is obese. In another data published by OECD, more than 50% of the European Union population is overweight or obese. Obesity prevalence rates are on the rise in China, India and Brazil, making more and more population suitable to insulin resistance. China is now the second obese country in the world followed by India. Adoption of sedentary life style due to and reduced physical activities are adding to worries. Various educational institutes are taking serious steps to curb child obesity by increasing physical activities in schools. These factors are expected to increase the prevalence of increase prevalence of insulin resistance in India, China and other countries. Developing healthcare sector, increasing per capita income and increasing awareness about medical treatments will drive the market in these countries. Reimbursement and other government policies governing pricing will also play a major role in determining the future of the market.

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The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.


Pharmaceutical Hot Melt Extrusion Market By Analysis of Major Industry Segments 2024

According to a new research report by Transparency Market Research (TMR), the degree of competition in the global pharmaceutical hot melt extrusion market is very high. The presence of a large number of participants characterizes the market, which demonstrates a fragmented landscape. Led by Leistritz AG, Milacron Holdings Corp., Xtrutech Ltd., Coperion GmbH, and Gabler GmbH & Co. KG, the market is expected to continue with intense rivalry between them in the near future. The leading players are likely to invest heavily in R&D initiatives over the years to come, in order to meet the demand of consumers by offering innovative products, states the report.

TMR estimates the opportunity in the global market for pharmaceutical hot melt extrusion, which was worth US$26.6 mn in 2015, to expand at a CAGR of 3.90% between 2016 and 2024 and reach a value of US$36.4 mn by the end of the period of the forecast. During the same period of time, the market volume is anticipated to swell at a CAGR of more than 4.7%, boosting the market significantly. Twin screw extruders have emerged as the most valued products in this market and is predicted to continue to enjoy a high demand over the forthcoming years.

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On Backdrop of Large Pool of Leading Players, North America to Retain its Lead

The worldwide market for pharmaceutical hot melt extrusion boasts of a widespread presence across North America, Asia Pacific, Latin America, Europe, and the Middle East and Africa. In this research report, a regional analysis of this market has also been provided to the readers. According to the study, North America led the global market with a share of nearly 38% in 2015. Researchers predicts this regional market to maintain its dominance throughout the forecast period, thanks to the presence of a large pool of established players, especially in the U.S.

The Europe market for pharmaceutical hot melt extrusion has also been witnessing steady growth and is predicted to continue doing so in the near future on account of the increasing demand for improved medical equipment and the growing adoption of extruders. Asia Pacific, However, will present the most lucrative growth opportunities for players in this market over the forthcoming years, thanks to rising number of research and development initiatives and the improving situation of the healthcare facilities in emerging economies, such as China, India, and Japan. The heightening standard of medical and healthcare infrastructure and the increase in government initiatives is also expected to impact this regional market in the forthcoming years.

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Rising Awareness among Consumers to Reflect Positively on Demand for Pharmaceutical Hot Melt Extrusion

According to an analyst at TMR, “the rising awareness regarding the benefits hot melt extrusion offers over traditional processing techniques, is the key factor behind the significant growth of the global pharmaceutical hot melt extrusion market.” The operating parameters in hot melt extrusion can be easily changed, the segmented screw elements allow agitator designs to be easily optimized to suit a particular application, and the die plates can also be easily exchanged to alter the extrudate diameter. All these characteristics are having a positive influence on the demand for pharmaceutical hot melt extrusion, leading to a significant rise in this market. However, the rising concerns over the quality and the non-compliance of regulatory requirements may limit the growth of this market to some extent over the next few years, notes the research study.

The study presented here is based on a report by Transparency Market Research (TMR), titled “Pharmaceutical Hot Melt Extrusion Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 – 2024.”


Patient Transport System Market: Industry Players Shifting Focus towards Developing Economies

Patient transport system enables and ensures on time delivery of medically ill, injured patients to health care organizations/institutions. Patient transport systems with significant resources and experienced staff have become an important and integral part of the health care sector. These systems are required by both critically ill, acute, chronic and non-urgent, planned patients for transport to and from hospitals, rehabilitation centers, clinics, nursing homes, and patient’s home. A patient transport system can be classified into two categories: emergency patient transport system and non-emergency patient transport system. The patient transport system market has experienced significant growth in the past few years and is expected to grow at a higher rate driven by increasing emphasis on improving value chain in the health care sector.

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The global patient transport system market has been segmented into emergency patient transport system and non-emergency patient transport system. Emergency patient transport system has been further segmented into ground ambulance services, air ambulance services, and water ambulance services. Based on equipment required during transportation, nature of injury and illness, the patient transport system market has been classified into advanced critical life support ambulance, basic life support ambulance, neonatal ambulance, cardiac ambulance, mobile dialysis ambulance, mobile delivery vans, mobile operation theatres, and air ambulances. Non-emergency transport system provides trips to and from scheduled medical appointments, interdepartmental transfers, and transfers between hospitals. It includes basic life support ambulances, wheelchairs, stretchers, first responder services (two wheelers), mobile beds, etc. In developed countries such as the U.S. and countries in Europe air ambulance, advanced critical life support ambulance, neonatal ambulance, and cardiac ambulance will grow at higher rates as compared to other segments.

Advancement of technology in patient transport system, high demand for safety features, increasing pressure for shortest call response time, and increasing number of cardiac, neonatal, and road accident patients are expected to drive the global patient transport system market. Demand for specialty ambulances for neonatal, cardiac, and gynecology patients is expected to be the key driver of the global patients transport system market. Air ambulance system plays a crucial role in minimizing time for transportation especially from remote locations. Government policies on meeting quicker health care facilities especially in remote areas are also anticipated to contribute to the growth of the global patient transport system market. Increasing number of chronic patients globally, growing emphasis on safety and quality features, upcoming technology with ease of access and improved comfort level, and government policies and regulations in non-emergency medical transport have triggered the growth of the non-emergency patient transport segment. Rising cost of technology and safety standards in non-emergency patient transfer especially in developing countries are the key restraints of the segment.

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Geographically, the global patient transport system market has been segmented into five regions: North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America and Europe are the major markets for patient transport system owing to high expenditure on health care services and advancement of technologies. According to Wall Street Journal blog, countries such as the U.S., China, and Australia were able to transport 75% of seriously injured road accident patients to hospital, whereas this rate was only 10% to 49% in India, Japan, and Pakistan. This blog highlights the scope and opportunity for the growth of patient transport system in Asia Pacific, the Middle East, and Africa. The market in Asia Pacific is expected witness the highest growth rate due to increasing number of road accidents, rising number of patients, incremental growth in the health care sector, and growing pressure to shorten the call response time.

Key players providing patient transport systems are National Medtrans Network, Falck A/S, Air Methods Corporation, Envision Healthcare Corporation, Acadian, NSL Limited, Airmed International LLC, and Airpal, Inc. Falck A/S dominated the emergency patient transport market with expansion plan in Asia Pacific, while NSL Limited is largest private non-emergency ambulance service provider in the U.K.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.


Single-use Bioreactors Market Dynamics and Opportunities Report by Transparency Market Research

Global Single-use Bioreactors Market: Overview

The use of single-use bioreactors across the global pharmaceutical industry has significantly increased since inception roughly two decades back. The market for these disposable bioreactors continues to tread along a healthy growth path as pharmaceutical companies begin to understand the immense flexibility and several other advantages associated with their use. For multi-drug producing pharmaceutical units, especially, single-use bioreactors mitigate the risk of cross-contamination and save significant time that is otherwise spent for cleaning and clearance validation to assure that no compounds are carried over from prior batches.

By lowering down the costs involved in cleaning and sterilizing bioreactors and increasing the operational flexibility of the entire drug manufacturing process, the use of single-use bioreactors leads to reduced capital expenditure costs. Owing to these factors, the preference for single-use bioreactors has significantly increased over the conventional stainless steel reactors in the past years.

An increasingly rising number of pharmaceutical companies are presently preferring the use of disposables for applications such as filtration, media preparation, purification, cell harvesting, virus inactivation, and buffer preparation. In the next few years, single-use bioreactors will play a central role in the pharmaceutical industry, supporting the need for the rapid development of novel drug varieties to tackle the vast array of diseases that are presently untreated or are becoming increasingly prevalent.

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Global Single-use Bioreactors Market: Scope of the Report

This report on the global market for single-use bioreactors presents a thorough overview of the market’s present state and a forecast regarding the future growth prospects of the market and its key segments over the period between 2016 and 2024. The report presents a thorough analysis of the key factors, such as drivers, challenges, past and present trends, competition, and regulatory landscape of the market, which are expected to have a notable influence on the future growth prospects of the market over the said period.

The report includes rich qualitative and quantitative data pertaining to these factors, gathered with the help of several primary as well as secondary research methodologies over the past few years. The report also includes an analysis of various market elements with the help of research methodologies such as Porter’s five forces analysis, which helps gauge the intensity of the key forces defining the competitive intensity and thus the attractiveness of a market for potential entrants.

The report also presents a detailed overview of the key micro and macroeconomic factors expected to have a wide-ranging impact on the market’s development over the period between 2016 and 2024. The report, with all this data, makes for a data repository that can aid companies in the market to formulate optimal growth strategies for promising returns in the field of single-use bioreactors.

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Global Single-use Bioreactors Market: Drivers and Restraints

The significantly rising cost pressures in the pharmaceutical industry and the increasing demand for new drug varieties to serve a vast number of new and untreated disease categories are compelling companies to reevaluating their operational and manufacturing processes. The use of single-use bioreactors is chiefly driven due to these pressures and an increasing number of pharmaceutical companies are adopting disposable bioreactors to speed-up the introduction of new product lines.

The market is witnessing significant developments in terms of materials, variety, and flexibility of bioreactors to be used across a large set of culture mediums. Several varieties of single-use technologies such as mixers, disposable vessels, and bioreactor bags have started to proliferate the market and an increasing number of manufacturers are venturing into to field to exploit the vast growth opportunities.

Global Single-use Bioreactors Market: Geographical and Competitive Dynamics

In terms of geography, the market for single-use bioreactors is presently dominated by North America and Europe owing to the presence of a large number of some of the world’s leading biopharmaceutical companies. In the near future, the market is also expected to witness promising growth opportunities in regions such as Asia-Pacific and Latin America as many international biopharmaceutical companies operate in these regions through large-scale manufacturing facilities in these regions.

The global market for single-use bioreactors market has become highly dynamic in the past few years, chiefly owing to new entrants and vast positive developments in the area of product variants. Some of the key vendors presently operating in the market are Sartorius Stedim Biotech, GE Healthcare, PBS Biotech, Thermo Fisher Hyclone, Merck Millipore, Xcellerex, and Cellexus Limited.


Essential Tremor Treatment with Ultrasound Market Outlook and Forecast up to 2024

Essential Tremors (ET) also known as benign tremor, familial tremor, and idiopathic tremor. Essential tremors are involuntary trembling in one or more parts of body. The cause of tremors is due to problems in parts of the brain that controls muscle in the body or in specific parts of the body, such as hands. It can also affect arm, head, eyes, face, vocal cord, trunk, and legs. Most tremors occur in the hands, which can impair patient’s ability to eat, shave, write, and perform household activities and functions in the workplace. Essential tremors are most common in people who are middle-aged and older, but anyone can suffer from this disorder. Treatment to relieve this disorder depends on their causes. Tremors can be treated by medicines or surgical procedure to improve muscles control. Essential tremors are not life threatening. However, they can be a cause of embarrassment and make it difficult to perform daily tasks. Treatment options for essential tremors are medication, deep brain stimulation (DBS), and thalamotomy. Medication is first line treatment option for essential tremors. Focused ultrasound is a completely non-invasive treatment of thalamotomy, which could be more effective than other methods. Focused ultrasound is performed when patients are awake and involves no anesthesia, no incision in the scalp, and no burr holes through skull or insertion of electrode through brain during the treatment. This provides a measure of safety because they can respond during the procedure. During focused ultrasound therapy, targeted cell in the thalamus are visualized in real time imaging. Focused beam of acoustic energy are used to heat and destroy target cells without impairing adjoining tissue.

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Essential tremors treatment with ultrasound market is supposed to be driven by factors such as increase in age related neurological disorder. FDA approvals for clinical trials and huge inflow of new players entering the market is leading can be factor for growth of essential tremor treatment market with ultrasound. Advanced technology, improved clinical outcomes and awareness regarding consumer preferences are factors that drive the growth of essential tremor treatment with ultrasound market. It is a non-invasive treatment that facilities patients to recover rapidly and perform day today task. Temporary sensory disturbances or lack of stability after treatment has been documented in can impact the growth of the market. Factor such as possibility of damage of other tissues can also restrain the growth of the essential tremor treatment with ultrasound market.

The global market of essential tremors treatment with ultrasound is segmented on the basis of indication end users and geographical region.

  • Segmentation by Indication
    • Head
    • Trunk
    • Upper Extremity
    • Lower Extremity
  • Segmentation by End User
    • Hospitals
    • Ambulatory Surgical Centers
  • Segmentation by Region
    • North America
    • Latin America
    • Europe
    • Asia Pacific
    • Middle East & Africa

According to American Academy of Neurology (AAN) conference report published in 2016 by Samantha J. Peterson, estimate that patients who have been treated with ultrasound for essential tremors have acknowledge around 50% development after 3 months and observed around 40% progress after a 10 months. International Essential Tremor Foundation estimated that 3% of population or approximately 10 million individuals in U.S. are affected by essential tremors in 2015. Based on indication the global market of essential treatment with ultrasound are segmented as Head, Trunk, Upper Extremity, and Lower Extremity. The Upper Extremity segment is expected to dominate the global market of essential tremor treatment with ultrasound. On the basis of end user, essential tremor treatment with ultrasound market is classified as Hospitals and Ambulatory Surgical Center. In this segment, ambulatory surgical center is expected to contribute maximum to the market share.

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On the basis of regional presence, the global Essential Tremor Treatment with Ultrasounds market is segmented into five key regions viz. North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America is expected to dominate the market of essential tremors with ultrasound due to factors such as sophisticated healthcare infrastructure and increasing awareness of patients and healthcare professionals. After North America, the essential tremor treatment with ultrasound market is expected to be dominated by Europe and Asia. Asia Pacific is the fastest growing region for essential tremor treatment market due to improving healthcare facility. In Asia Pacific region, developing countries such as India and China are expected to offer good opportunities for the global Essential Tremor Treatment with Ultrasound market due to rising expenditure levels for significant growth.