Category Archives: Biotechnology

Single-Use Bioreactors Market Estimated to Experience a Hike in Growth by 2026

Single-use bioreactors available today are robust and offers high performance which is necessary for the commercial manufacturing of biopharmaceutical products. Improvements in the bioreactor designs, film technology, sensor systems and stirring mechanisms are resulting in the increasing adoption of the single-use bioreactors. Manufacturers are also closely working with their customers to comply with the changing needs such as for next-gen gene and cell therapies, and for continuous bioprocessing. New generation single-use bioreactors are being designed while keeping in mind the processes and final drug product perspectives by the end users.

Recent developments in single-use bioreactors by manufacturers are focused on improving mixing, reducing complexity, and avoid leakage and integrity issues. Improvements in the cell-culture processes are also leading to the rise in adoption of single-use bioreactors.

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Some of the key market players in the report are Sartorius Merck Millipore, Stedim Biotech, GE Healthcare, Thermo Fisher Scientific, Danaher, Parker Hannifin, Eppendorf, Applikon Biotechnology, Cesco Bioengineering, Celltainer Biotech, Cellexus, PBS Biotech, Distek, Pierre Guerin, and Solida Biotech.

Global Single-Use Bioreactors Market to Witness Strong Growth during the Forecast Period 2017-2026

According to the latest report compiled by Transparency Market Research (TMR), the global single-use bioreactors market is expected to witness robust growth. It is also estimated to increase to 13.5% CAGR throughout the forecast period 2017-2026. The market is also projected to reach US$ 1,547.3 million revenue by 2026 end.

The global single-use bioreactors market is segmented on the basis of product type, cells type, end user and molecule type. Based on the product type, the segmentation consists of media bags, single use bioreactor systems and filtration assemblies. Among these, single use bioreactor systems are anticipated to witness significant growth throughout the forecast period. Based on the cells type, the market is categorized into bacterial cells, mammalian cells, yeast cells, and others. Between 2017 and 2026, mammalian cells are expected to witness the highest growth.

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By end user, biopharmaceutical companies are anticipated to emerge as the largest users of the single-use bioreactors during 2017-2026. In the terms of molecule type, the segment includes gene-modified cells, stem cells, vaccines, monoclonal antibodies (MABS) and others. Among aforementioned molecule types, monoclonal antibodies (MABS) is likely to witness strong growth in the global single-use bioreactors market between 2017 and 2026.

Europe to Emerge as the Most Lucrative Market in the Global Single-Use Bioreactors Market

Europe is anticipated to be the most dominating region in the global single-use bioreactors market during 2017-2026. Owing to the presence of some of the world’s leading pharmaceutical companies in Europe, the region is likely to witness growth. The region is expected to account for the largest share, due to the patient cliff of many biologics drugs in the region and the strong support by the government to the biopharmaceutical companies in order to establish new therapies in biologics. Also, the increasing use of single-use bioreactors in cell culture-based manufacturing is driving the demand in the region. Single-use bioreactors are also becoming technologically advanced and are also being provided at competitive cost.

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Meanwhile, North America and APEJ are also likely to witness growth in the single-use bioreactors market. Increasing investment by biopharmaceutical companies to establish their manufacturing facilities is driving the growth in APEJ. Increasing focus on research activities and well-established healthcare industry is resulting in the growth of the market in North America.

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Carbon Dioxide Incubators Market Set to Witness an Uptick during 2017 – 2026

A new report composed by Transparency Market Research (TMR) provides insights and analysis on the global carbon dioxide incubators market for the forecast period – 2017 to 2026. The report has profiled prominent players actively contributing to the market growth, and has tracked their occupancy using an intensity map. Key market players identified by the report include Shanghai Boxun Medical Biological Instrument Corp., LEEC Limited, Bellco Glass, Inc., Memmert GmbH + Co. KG, BINDER GmbH, Sheldon Manufacturing, Inc., Eppendorf AG, Panasonic Healthcare Co., Ltd., and Thermo Fisher Scientific Inc.

Presence of numerous vendors has made the global carbon dioxide incubators market’s nature to be fragmented, albeit product offerings of these vendors are similar to an extent in terms of design and functionality. The market is less competitive on the back of slow technology upgradation cycle regarding carbon dioxide incubators. Global leading vendors of carbon dioxide incubators are adopting after sales services and streamlined distribution systems for retaining their dominance in the market.

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Increasing Technological Penetration in Production of Carbon Dioxide Incubators – Key Growth Driver

Global market for carbon dioxide incubators is projected to register a splendid expansion through 2026. Worldwide sales of carbon dioxide incubators are estimated to account for roughly US$ 300 Mn revenues by 2026-end. Increasing technological penetration in the production of carbon dioxide incubators is considered to be one of the key growth drivers for the market. A great example for this is the introduction of an advanced version of carbon dioxide incubator equipped with HEPA filters and infrared radiation control, which offers results with enhanced quality. With laboratories taking efforts toward incorporating automation, demand for carbon dioxide incubators will witness a consistent rise in the near future. Future of the market for carbon dioxide incubators is centered upon upgradation to newer application-specific products equipped with more sophisticated features.

However, high prices of carbon dioxide incubators are expected to remain a major factor restraining their adoption. Customization requirements based on working environment which include additional shelves & trays, or add-on accessories, along with their service, maintenance, and repair further add to the cost of these incubators. Market players emphasizing on development of technologically sound and cost-effective carbon dioxide incubators for high quality outputs are likely to witness lucrative growth opportunities in the foreseeable future.

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North America to Remain Largest Market for Carbon Dioxide Incubators

In terms of revenues, North America is likely to remain the largest contributor to growth of the global carbon dioxide incubators market, followed by Europe. Revenues from the markets in North America and Europe are collectively projected to account for over half share of the market by 2026-end. Asia-Pacific excluding Japan (APEJ) is projected to register a double-digit CAGR through 2026, and is anticipated to remain the fastest expanding market for carbon dioxide incubators, followed by North America.

On the basis of product type, water jacketed carbon dioxide incubators will continue to be sought-after among end-users, with sales poised to account for nearly US$ 200 Mn by 2026-end. Revenue share of water jacketed carbon dioxide incubators in the market will remain considerably higher than combined revenue share of air jacketed and direct heat carbon dioxide incubators.

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Above 200L Capacity of Carbon Dioxide Incubators to Remain Preferred

Carbon dioxide incubators with capacity of above 200L will remain preferred in the market. However, sales of carbon dioxide incubators with capacity of above 100L & below 200L are projected to register the fastest expansion in the market through 2026. In addition, revenues from sales of carbon dioxide incubators having below 100L capacity are expected to remain sluggish during the forecast period.

Although laboratory research and clinical applications of carbon dioxide incubators are expected to remain the most financially rewarding, in vitro fertilization application of these incubators will register a relatively higher CAGR through 2026. However, revenues from the former will remain significantly larger than the latter throughout the forecast period.

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Membrane Separation Systems Market Estimated to Experience a Hike in Growth by 2025

Amidst a fragmented vendor landscape in the global membrane separation systems market, large players that operate globally have been observed to hold supremacy in the overall market, as per one of the current reports by Transparency Market Research (TMR). In a typical scenario in this market, small scale vendors operate in regional markets serving a few end-use industries, whereas market leaders such as The Dow Chemical Company and Koch Membrane Systems Inc. not only operate globally but have serve a number of end-use industries. The topnotch companies are also upping spends on research and development to introduce innovative systems.

Pall Corporation, Sartorius AG, 3M, Amazon Filters, Advantec MFS Inc., GE Healthcare, Merck Millipore, Novasep, and TriSep Corporation (Microdyn-Nadir US, Inc.) are to name some other prominent companies in the global membrane separation systems market.

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As per estimates of a report by Transparency Market Research (TMR), the global membrane separation systems market will clock a CAGR of 9.3% for the forecast period from 2017 to 2025. Expanding at this rate, the market’s valuation of US$28,134.4 mn in 2016 will become US$61,801.9 mn by the end of 2025.

The microfiltration segment, among the key technology segments, held the leading share in the global membrane separation systems market in 2016. By application, the environmental segment holds the leading share among other segments in the membrane separation systems market. Europe held the commanding share vis-à-vis revenue in the global membrane separation systems market among other key regions in 2016.

Measures to Save Water and Interest for Wastewater Treatment Stokes Demand

Amongst several driving factors, a significant part of the demand for membrane separation systems originates from municipal corporations. At present, measures for water reuse and wastewater treatment to save wastage of the essential commodity is the consideration of environmental agencies. This has boosted the uptake of membrane separation technologies, which in turn is stoking demand for membrane separation systems.

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In particular, emerging economies that are underway rapid industrialization and facing population explosion in water-stressed areas are expected to augment the growth of this market in the upcoming years.

Membrane separation technology has emerged as the most important separation technology over the last couple of years. This is because membrane separation technology is free of chemicals, consumes less energy, and operates in an organized manner, which conventional separation techniques lack. Due to the distinct offerings of membrane separation technology, it is increasingly being used for different processes in water management, wastewater and process water treatment, food and beverage, life sciences, and pharmaceutical industries. The technology is also used for separation processes in chemical, petrochemical, and manufacturing industries.

Apart from this, several governments and metropolitan planners are awakening to the impact in the event of a shortage of water which is an everyday essentiality. This is pushing the need for innovations for water treatment, thereby paving way for the growth of the worldwide market for membrane separation systems.

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High Set-up and Operational Costs Crimps Growth

However, on the downside, high establishment and operational costs, insufficient infrastructure, and availability of other water cleaning and treatment procedures are posing a challenge to the growth of membrane separation systems market.

The information presented here is based on the findings of a TMR report, titled “Membrane Separation Systems Market (Technology – Microfiltration, Ultrafiltration, Nanofiltration, Reverse Osmosis, Chromatography, and Ion Exchange; Application – Environmental, Food & Beverages, and Healthcare; Material – Polyethersulfone, Polysulfone, Cellulose Based, Nylon, Polypropylene, Polyvinylidene Fluoride, Polytetrafluoroethylene, Polyacrilonitrile, and Polyvinyl Chloride) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2017–2025.”

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Blood Transfusion Diagnostics Market Outlook Key Analysis and Forecast by 2025

A recent intelligence study by Transparency Market Research (TMR) has detected that the global blood transfusion diagnostic market is highly fragmented in nature, owing to the participation of many local and regional players. As per the report’s findings, the top four companies didn’t even account for one-third of overall shares of the global blood transfusion diagnostics market in 2016. Apart from a few major companies, such as Immucor Inc., Ortho-Clinical Diagnostics, Inc., Bio-Rad Laboratories, Inc. Abbott Laboratories, Quotient, Ltd., BAG Health Care GmbH, Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., and Hologic, Inc., most of the smaller players offer their products regionally and locally. Immucor Inc. currently accounts for the most prominent share in the global blood transfusion diagnostic market, at 11.6% in 2016, owing to its wide offerings in transfusion, transplant, and molecular diagnostics. Robust portfolio of products and solutions keeps Ortho-Clinical Diagnostics, Inc. in good stead in the global blood transfusion diagnostics market.

This 156 page report gives readers a comprehensive overview of the blood transfusion diagnostics market. Browse through 30 data tables and 83 figures to unlock the hidden opportunities in this market:

As per the estimations of the TMR report, the demand in the global blood transfusion diagnostics market will increment at a healthy CAGR of 6.8% during the forecast period of 2017 to 2025, reaching a valuation of US$6.0 bn by the end of 2025, significantly up from its evaluated worth of US$3.3 bn in 2016. As far as recent market developments is concerned, Abbott Laboratories and St. Jude Medical, Inc., announced definitive agreement for Abbott to acquire St. Jude Medical, creasing a premier medical device leader with top positions and high growth worldwide. BAG Health Care GmbH launched a new BAGene kid and a new BAGene format to improve the results of its existing product BAGene SSP kit.

In terms of revenue, the kits and reagents segment of product type is anticipated to dominate the market during the forecast period, whereas application-wise, blood grouping is losing shares owing to technological advancements towards automation. Hospitals are expected to remain the most profitable end-users, by a long margin. Geographically, North America accounted for 43.1% share of the total market in 2016.

Escalating Blood Transfusion Procedures Driving Demand

Increasing number of blood transfusion procedures is the key factor augmenting the demand in the global blood transfusion diagnostics market. According to the American National Red Cross, approximately 21 million blood components are transferred in the U.S. each year. Over 90,000 people are affected by sickle cell disease in the U.S. and blood transfusion is a frequent process in sickle cell patients. In addition to that, the World Health Organization estimates that around 16 countries across the world have inadequate facilities for screening donated blood for one or more infections. This shortage is attributed to the irregular supply of test kits. Rapid technological advancement and automation in blood processing equipment, which can reduce the contamination risk associated with the collection and handling procedures, shortage of blood transfusion infrastructure in developing countries, increasing government awareness programs and incentives for blood transfusion and donation, and the development of the WHO recommended national blood policy.

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Low Blood Donation Rate Obstructing Market Prosperity

On the other hand, low blood donation rate and stringent regulation related to safe blood transfusion are a few hindrances faced by the global blood transfusion diagnostics market. The report observes that although blood donation is a remarkably safe medical procedure, lack of knowledge and beliefs obstructs potential blood donors from obliging. In addition to that, high investment and steep operational costs restrain emerging economies such as Brazil, India, China, and Indonesia from adopting new blood processing technologies. That being said, persistent awareness programs by various health organizations and government agencies is expected to somewhat overcome this restraint over the course of the forecast period.

The information presented in this review is based on a Transparency Market Research report, titled, “Blood Transfusion Diagnostics Market (Product Type – Kits & Reagents and Instruments; Application – Blood Grouping and Disease Screening (Molecular Disease Screening and Serological Disease Screening); Distribution Channel – Hospitals, Diagnostic Laboratories, and Blood Banks) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 – 2025.”


Separation Systems for Commercial Biotechnology Market Trends, Regulatory Landscape and Operational Strategies 2023

The leading players, including Danaher Corporation, Thermo Fischer Scientific Inc., and Waters Corporation are putting in constant efforts to enhance their product portfolio in order to stay ahead in the global separation systems for commercial biotechnology market. These players are primarily capitalizing on prominent product segments such as liquid chromatography and flow cytometry to improve their visibility in the market, finds Transparency Market Research in a new study. The presence of a large number of players in the market is resulting in price wars.

High Government Funding in Biotechnology Sector Fuels Growth of North America

On the basis of end user, the life sciences research and diagnostics segment will continue to remain at the forefront of the market until 2023. The growing research in the field of genomics and proteomics is boosting the demand for MACs and FACs and microarray instruments in life sciences research and diagnostics sector. Owing to this factor, the segment is poised to expand at a CAGR of 7.6% during the review period.

This 102 page report gives readers a comprehensive overview of the separation systems for commercial biotechnology market. Browse through 8 data tables and 15 figures to unlock the hidden opportunities in this market:

Geographically, North America will continue to be the leading revenue contributor until 2023, accounting for 40.7% of the overall market. The domicile of a large number of key players provides a competitive edge to the region. Moreover, high government funding for research activities in the field of biotechnology is triggering the adoption of separating systems. Asia Pacific is estimated to post a CAGR higher than any other region during the same period, due to the increasing government support and growing investments by global participants.

Continuous Innovations in Various Separation Systems Impact Market Growth Positively

Technological advancements in various types of separation systems are providing a significant boost to the global market for separation systems for commercial biotechnology. Techniques such as liquid chromatography, flow cytometry, and microarray are gaining popularity with continuous innovations in them. “These technological innovations support quick and effective separation of molecules, thereby driving their adoption,” says a TMR analyst.

In addition, advancements in commercial biotechnology are stirring up the demand for automated separation systems. This is encouraging greater investments in research and development activities in separation systems, thereby escalating the growth of the market. Another factor that is augmenting the market is the increasing number of conferences worldwide by various private and government organizations, as these conferences help in stimulating awareness among end users regarding new separation systems.

High Cost of Chromatography Systems Hinders Market Growth

The high cost of chromatography systems and technologies is resulting in a shift in preference towards alternatives such as microextraction and electrophoresis-based techniques. Additionally, the designing and incorporation of automated features in the systems are capital-intensive, which increases the price of the whole separation systems. Thus, the high cost of these systems is hampering the growth of the global separation systems for commercial biotechnology market.

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Moreover, magnetic activated cell sorting (MACS), a technology which is considered as gold standards for cell separation, is invented and patented by Miltenyi Biotec GmbH. This is restricting the entry of new players, which in turn is acting as an impediment to the growth of the global separation systems market. However, the improving healthcare infrastructure and rising disposable income of the people in emerging economies are opening new avenues for market players.

The above data has been derived from a report by TMR, titled “Separation Systems for Commercial Biotechnology Market (Product – Liquid chromatography, membrane filters, electrophoresis instruments, flow cytometer instruments, centrifugation systems, DNA microarray instruments, protein microarray instruments, MACS & FACS systems, and biochips and lab-on-a-chip; End User – Life Sciences Research and Diagnostics, Pharmaceuticals, Food & Cosmetics, Energy, and Agriculture) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015-2023.”