Category Archives: Biotechnology

Separation Systems for Commercial Biotechnology Market Trends, Regulatory Landscape and Operational Strategies 2023

The leading players, including Danaher Corporation, Thermo Fischer Scientific Inc., and Waters Corporation are putting in constant efforts to enhance their product portfolio in order to stay ahead in the global separation systems for commercial biotechnology market. These players are primarily capitalizing on prominent product segments such as liquid chromatography and flow cytometry to improve their visibility in the market, finds Transparency Market Research in a new study. The presence of a large number of players in the market is resulting in price wars.

High Government Funding in Biotechnology Sector Fuels Growth of North America

On the basis of end user, the life sciences research and diagnostics segment will continue to remain at the forefront of the market until 2023. The growing research in the field of genomics and proteomics is boosting the demand for MACs and FACs and microarray instruments in life sciences research and diagnostics sector. Owing to this factor, the segment is poised to expand at a CAGR of 7.6% during the review period.

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Geographically, North America will continue to be the leading revenue contributor until 2023, accounting for 40.7% of the overall market. The domicile of a large number of key players provides a competitive edge to the region. Moreover, high government funding for research activities in the field of biotechnology is triggering the adoption of separating systems. Asia Pacific is estimated to post a CAGR higher than any other region during the same period, due to the increasing government support and growing investments by global participants.

Continuous Innovations in Various Separation Systems Impact Market Growth Positively

Technological advancements in various types of separation systems are providing a significant boost to the global market for separation systems for commercial biotechnology. Techniques such as liquid chromatography, flow cytometry, and microarray are gaining popularity with continuous innovations in them. “These technological innovations support quick and effective separation of molecules, thereby driving their adoption,” says a TMR analyst.

In addition, advancements in commercial biotechnology are stirring up the demand for automated separation systems. This is encouraging greater investments in research and development activities in separation systems, thereby escalating the growth of the market. Another factor that is augmenting the market is the increasing number of conferences worldwide by various private and government organizations, as these conferences help in stimulating awareness among end users regarding new separation systems.

High Cost of Chromatography Systems Hinders Market Growth

The high cost of chromatography systems and technologies is resulting in a shift in preference towards alternatives such as microextraction and electrophoresis-based techniques. Additionally, the designing and incorporation of automated features in the systems are capital-intensive, which increases the price of the whole separation systems. Thus, the high cost of these systems is hampering the growth of the global separation systems for commercial biotechnology market.

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Moreover, magnetic activated cell sorting (MACS), a technology which is considered as gold standards for cell separation, is invented and patented by Miltenyi Biotec GmbH. This is restricting the entry of new players, which in turn is acting as an impediment to the growth of the global separation systems market. However, the improving healthcare infrastructure and rising disposable income of the people in emerging economies are opening new avenues for market players.

The above data has been derived from a report by TMR, titled “Separation Systems for Commercial Biotechnology Market (Product – Liquid chromatography, membrane filters, electrophoresis instruments, flow cytometer instruments, centrifugation systems, DNA microarray instruments, protein microarray instruments, MACS & FACS systems, and biochips and lab-on-a-chip; End User – Life Sciences Research and Diagnostics, Pharmaceuticals, Food & Cosmetics, Energy, and Agriculture) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015-2023.”

 

Increasing Consumption of Antibiotics Worldwide to fuel Demand for Microbiology Culture, states TMR

The global microbiology culture market has been predicted by Transparency Market Research (TMR) to uphold a moderately fragmented arrangement for its vendor landscape due to a substantial count of regional and international participants. In the past, top four companies, viz. Becton, Dickinson and Company, Merck Millipore, Thermo Fisher, and Sigma-Aldricha, had raked in a more than 50.0% share in the global microbiology culture market. With a view to attain a competitive edge in the global microbiology culture market, companies could take to achieving new breakthroughs and making novel discoveries in the industry. The level of competition, however, has been anticipated to stay high in the global microbiology culture market.

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According to a market intelligence publication authored by TMR, the global microbiology culture market could expand at a decent CAGR of 5.90% during the forecast period 2015–2023. This has been envisaged to help the global microbiology culture market improve its revenue valuation to around US$7.5 bn by the final forecast year. Foreseen to be immediately followed by special media, complex media could secure its position as one of the most preferred culture media until the next few years. Asia Pacific has been envisioned to register a faster CAGR of 6.80% by the end of the forecast period.

Need for Antibiotics Production on Large Scale Augments Microbiology Culture Demand

The increasing practices of microbiology culture on account of an aggressive demand for antibiotics could be key for the rise of the world microbiology culture market. Produced by microorganisms, antibiotics as secondary metabolites are extensively used in the treatment of various protozoan and bacterial infections. Since antibiotics occur naturally, their available quantity in the natural environment does not match with the quantity required for large-scale production. This has been foretold to intensify the requirement of microbial culture for obtaining antibiotics.

In the coming years, the demand for microbial culture could increase with the elevating consumption of antibiotics triggered by surging access to antibiotic drugs, improving healthcare expenditure, and telling frequency of infectious diseases. Furthermore, the BRICS economies that have secured a significant share in the consumption of antibiotics over the last decade, according to the Lancet Infectious Diseases Commission, have been prognosticated to raise the hopes of players functioning in the world microbiology culture market.

Expensive and Continual Functioning of Fermentation Vessels Increases Costs

High costs associated with culture media and the requirement of continual running of fermentation vessels over several weeks have been projected to impede the rise of the worldwide microbiology culture market. Producers of antibiotics could find it difficult to curb the cost of fermentation operated on a large scale. Moreover, alternative nutrient sources essential for the growth of various microorganisms have been forecasted to be difficult to identify, which could delay the growth in the worldwide microbiology culture market.

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However, the emergence of recombinant technology has been prophesied to bode well for players looking to improve their share in the worldwide microbiology culture market. Besides this, players could take advantage of the unmet medical needs in emerging nations and increasing growth of the worldwide microbiology culture market in developed regions owing to increased government funding. Apart from hospitals and laboratories, the food sector has been foreseen to increase the demand for microbial culture.

The information presented in this review is based on a TMR report, titled, “Microbiology Culture Market (Culture – Bacterial Culture and Eukaryotic Culture; Media – Simple Media, Complex Media, Synthetic Media, and Special Media) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015 – 2023.”

 

Mice Model Market: Expected Advancements & Global Industry Analysis 2023

Global Mice Model Market: Snapshot

Biomedical research has taken a front seat in the healthcare and pharmaceutical industries, to a point where a nation’s research and development landscape can be gauged by its level of investment in biomedical research. The past decade has consequently witnessed a staggering rise in biomedical research in most countries, both developed and developing. A significant part of this research investment typically goes into animal models, more specifically, mice models. This forms the primary driver for the global mice models market.

Another factor promoting the increased use of mice models is the recent number of improvements that have been made in mice models. These improvements have not only enhanced their utility in current applications, but also increased the overall scope of applications for mice models. Biomedical research can use mice models for increasingly complex diseases, such as the use of mutated mice models for studying the ALS disease, or the use of advanced mice models to understand lung injury repair.

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The factors above and similar ones that promote the use of mice models are responsible for imparting a positive growth rate to the global mice models market, which is expected to be valued at US$1.79 bn by the end of 2023.

Demand for Mice Models in North America Remains High

44.9% of the global market for mice models is expected to be held by North America in 2023, in terms of revenue. Europe at the same time is expected to emerge as the second-leading market for mice models, followed closely by Asia Pacific. North America and Europe have an established pharmaceutical industry and an advanced biosciences research field. Both regions are still showing a high demand for mice models that are meant to be used in advanced drug discovery processes and other medical research.

However, their overall share in the market value has dropped since 2014, owing to the significantly high demand for mice models in Asia Pacific. This region is showing an especially high demand for knockout and transgenic mice models. Close to half of the global mice models business in the world for these types is taken up by the Asia Pacific countries of China, India, Malaysia, and Singapore.

Inbred Mice Models Continue to Show High Demand, Demand for Hybrid Models on the Rise

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Based on model types, the global market for mice models is expected to progress at a CAGR of 6.4% from 2015 to 2023, ending at US$1.79 bn by the end of 2023. Among the various mice model types, inbred mice models have consistently been the popular ones, owing to the ease with which scientists can reproduce the data and the overall cost effective system of obtaining inbred mice models. Additionally, the size of samples in inbred mice models can be considerably smaller than their outbred counterparts.

However, the demand for congenic or hybrid mice models is expected to rise significantly over the coming years owing to a high preference for them in the expanding cardiovascular research. Transgenic mice models are the second most popular models in the world. They possess a high volume of research capability in the fields of angiogenesis, breast cancer, and Alzheimer’s disease.

The key providers of mice models from a global standpoint include Charles River Laboratories, The Jackson Laboratory, Harlan Laboratories, and Taconic Biosciences.

 

Bone Morphogenetic Proteins Market Overview – Key Futuristic Trends And Competitive Landscape 2022

A new Transparency Market Research report states that the global bone morphogenetic protein market was valued at US$612.601 mn in 2013.and is predicted to reach US$587.069 mn by 2022. It is expected to expand at a sluggish CAGR of 2.10% from 2014 to 2022. The title of the report is “Bone Morphogenetic Proteins Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2014 – 2022”.

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According to the report, the market for bone morphogenetic proteins is fuelled by the growing geriatric population, increasing sports and trauma injuries, and the increasing count of spinal fusion surgeries. In addition, the growing demand for minimally invasive surgeries and a rise in population having lower back pain issues will also augment the demand for bone morphogenetic proteins. On the other hand, factors such as the presence of a number of other bone graft substitutes and the detrimental side-effects caused by the off-label usage of bone morphogenetic proteins may impede the growth of the market in the coming years. Furthermore, the soaring costs of bone morphogenetic proteins may also pose a negative effect on the growth of the market.

The report segments the market on the basis of type into rhBMP-2 and rhBMP-7. Amongst these, in 2013, the segment of rhBMP-2 held the largest share in the market on the basis of revenue. This is because rhBMP-2 has been broadly accepted by surgeons and physicians globally owing to it being effective in carrying out lower back spinal fusions. On the other hand, the segment of rhBMP-7 is predicted to lose all of its market share in the forthcoming years owing to the elimination of OP-1/Opgenra from the market, starting from August 2014.

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On the basis of application, the report segments the market into trauma, spinal fusion, oral maxillofacial, and reconstructive surgery. Amongst these, the segment of spinal fusion holds the largest share in the market, trailed by the segment of trauma. On the other hand, the reconstructive segment is predicted to expand at low CAGR in the forecast horizon. This is owing to the availability of a number of promising bone graft alternatives and the limited utilization of bone morphogenetic protein products in reconstructive surgery.

On the basis of geography, the bone morphogenetic proteins market is segmented into Europe, North America, Asia Pacific, and Rest of the World (RoW). Amongst these, North America constitutes the largest share of more than 70% in the market for bone morphogenetic proteins and is predicted to lead the market all through the forecast horizon. This is due to the increasing awareness on bone morphogenetic protein products and the rising count of spinal fusion procedures.As per the report, the chief players operating in the market are Medtronic, Cellumed Co. Ltd., and Stryker Corporation, among others.

 

Transformative Effect of Regenerative Medicine on Human Health Benefits Global Market

Global Regenerative Medicine Market: Snapshot

Increasing application areas such as neurology, cardiovascular, musculoskeletal and orthopedic diseases will build up greater opportunities, states TMR. The market for regenerative medicine market appears to be fragmented in terms of competition. The Asia Pacific region will present large opportunities, displaying a promising CAGR between 2013 and 2019. The Asian countries such as South Korea, China, and Japan hold considerable prospects for augmentation of global regenerative medicine market. Smith & Nephew, a British medical equipment manufacturing company acquired Sushrut Surgical Pvt. Ltd., an India-based medical technology firm, enhancing access to the consumer pool in Asian countries in order to secure larger profits.

The global regenerative medicine market was pegged at US$2.5 mn in 2012. It is projected to achieve US$6.4 mn by the end of 2019, expanding at a progressive CAGR of 12.8% during the forecast period.

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North America Leads Due to Increasing Bone and Joint Reconstructive Surgeries

North America, owing to a large number of leading companies operating in regenerative medicine, dominates the global regenerative medicine market. The ongoing expansive research and development activities in the U.S. will also drive the North America segment. The bone and joint regenerative medicine market is the leading application segment in this region, as a high demand for regenerative medicine is exhibited.

The region of Asia Pacific will witness monumental growth because of its massive consumer pool, rising disposable incomes of people, and growing healthcare expenditure. Over the coming years, the regenerative medicine market in Asia Pacific will benefit from the growing demand for orthopedic surgeries, technological innovations, high incidence of joint and bone diseases, and increasing awareness about regenerative medicine. However, the market might face challenges such as high costs and regulatory policies.

Japan displays great potential on account several favorable factors. Fewer regulatory restraints, coupled with technological advancements in the area of regenerative medicine will ensure market expansion in the country. One key technological development is the emergence of 3D tissue bioprinters that enable the creation of blood vessels, cartilage, skin and other tissues.

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Extensive Research in Stem Cell Therapy to Promote Growth

Bio-based alternatives such as stem cell therapy and tissue engineering have gained prominence despite the rapid development of synthetic options. The high generative power of stem cells enables the production of other cells in the body. This feature of stem cells has raised demand for stem cell therapies. Additionally, stem cell therapy is used in the treatment of diseases such as cancer, retinal diseases, Alzheimer’s, diabetes, heart failure treatment, rheumatoid arthritis, autism spectrum, multiple sclerosis, cerebral palsy, and osteoarthritis, among others. It is projected that stem cells will occupy an important portion of regenerative medicine market over the coming period. Therefore, large-scale research activities have been undertaken in order to tap their full potential. However, factors such as ethical issues related to the use of embryonic stem cells might pose a threat to further expansion.

Notwithstanding the advancement of the stem cell therapy segment, the biomaterials segment is expected to retain its foremost position in the global regenerative medicine market. The largest amount of shares were held by this segment in 2012 on account of great demand for biomaterials and supportive reimbursement policies.

The key players operating in the global regenerative medicine market are Stryker Corporation (Vitoss Bone Graft Substitute), DePuy Synthes, Inc. (Healos Bone Graft), CONMED Corporation, Arthrex, Inc., Zimmer Holdings, Inc. (CopiOs Bone Void Filler), and Medtronic, Inc.(INFUSE Bone Graft).