Author Archive: Research Reports Industry

Vascular Graft Market Outlook to 2023 Latest Industry Forecast Report

Vascular surgical procedure remains often invasive and needs prolonged hospital stays. Conventional vascular surgery comprises of opening the body, cutting vessels, and closing it by means of sutures, it consist of procedures such as carotid endarterectomy, open abdominal aneurysm repair and lower extremity bypass surgery. In contrast, majority of vascular graft procedures are usually are minimally invasive besides involve repairing vessels from inside. Catheter-based devices are introduced through a minor incision and are directed with the aid of real-time imaging technologies. Typical endovascular procedures comprises of stenting, angioplasty, stent-grafting, and atherectomy.

Vascular graft is a medical procedure that is done to redirect the flow of blood in an area of the body and is generally performed due to the insufficient blood flow and as a part of organ transplantation. In general, a person’s own vein is chosen as a graft material or other synthetic materials such as Dacron, ePTFE or a different person’s vein are also generally used. Moreover, can also be redirected and serve as vascular grafts. An ideal vascular graft consist of the following characteristics such as appropriate size to match the host vessels, rapid healing, ease of handling, increased porosity, resistance to infection, low thrombogenicity and economical

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The global vascular graft market is segmented based on types, products, application and geography. The vascular grafts are of various types such as autologous, preserved autologous and synthetic. The autologous includes saphenous veins and radial artery; preserved autologous includes cryopreserved veins, whereas the synthetic grafts consist of PTFE, Teflon and Dacron. The PTFE has gained more popularity over Dacron due to the better tissue adhesion, improved pliability and lack of requirement to preclot prior to implantation. The products include endovascular stent graft, peripheral vascular graft, hemodialysis access graft and coronary artery bypass graft. The endovascular stent graft is known to have a largest market share in this segment due to high volume of EVAR (endovascular aortic repair) procedures. The applications include cardiovascular diseases, kidney failure, vascular occlusion, aneurysm, diabetes and others.

Based on the geography, market segmentation is North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. North America dominates the vascular graft market due to the presence of advanced healthcare infrastructures, reimbursement policies and adoption of new innovative products. However, Asia Pacific is expected to be the fastest growing in the vascular graft market due to the government initiatives and fast development in the research facilities.

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Some of the factors such as rise in the healthcare expenditures, increasing demand of minimally invasive procedures, increase in the prevalence of cardiovascular diseases, ageing population are some of factors responsible to drive the global vascular graft market. However, sometime the failure of the products and alternative therapies acts as a restrain or hinders the growth of the market. The rise in the unhealthy lifestyle of the people and reimbursement policies in the developed nations will create an opportunity to vascular graft market.

Some of the key players in the vascular graft market are Medtronic Plc., Bard Peripheral Vascular Inc., W.L. Gore & Associates, Inc., Cook Medical, LeMaitre Vascular Inc. Humacyte, Inc. and Terumo Medical Corporation, and B. Braun.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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ECG Systems Market Outlook to 2024 Latest Industry Forecast Report Available Online by Tranparency Market Research

Global ECG Systems Market: Description

Electrocardiography (ECG) is a way of measuring the electrical activity of the heart. During each heartbeat, cardiac muscles undergo depolarization, creating a small electrical charge. This charge, the frequency and magnitude of which serves as a sign of heart health, is detected via electrodes on the chest and limbs. ECG systems allow cardiologists to diagnose several cardiac conditions, such as arrhythmias, congenital cardiac problems, and poor blood supply. The ease of conducting an ECG test has led to it becoming widely used for primary cardiologic diagnosis.

Global ECG Systems Market: Drivers

The primary driver for the global ECG systems market is the increasing prevalence of cardiovascular diseases. The increasing acceptance of the Western lifestyle in developing regions such as Asia Pacific and Latin America has led to an increasing prevalence of lifestyle disorders such as diabetes and obesity, which are major risk factors for cardiovascular diseases. Cardiac diseases are already among the deadliest groups of diseases across the world and are expected to increase in morbidity in the coming years due to the increasingly sedentary lifestyle of the modern populace. This will likely propel the global ECG systems market at a brisk pace.

Steady technological innovation in medical devices, required to iron out the tiniest of flaws and make vital medical devices as precise as possible, has led to the development of advanced ECG systems that monitor cardiac activity with a high degree of precision. This has made diagnosis through ECG systems increasingly reliable, consequently increasing patient confidence and thus driving the global ECG systems market.

Several governments across the world have been proactive in establishing advanced, modernized health-care networks. This has led to steady government support for the development of disease monitoring devices that can provide accurate diagnoses and thus help reduce the incidence of diseases. This has worked in favor of the global ECG systems market in the past few years and is expected to remain an influential factor in the coming years.

Global ECG Systems Market: Restraints and Opportunities

On the flip side, the instability of economic conditions in many parts of the world and the lack of promising reimbursement policies are the major restraints on the global ECG systems market. The ECG systems market has also suffered from saturation in developed economies, where healthcare networks have already reached a high level of sophistication. However, the rising demand for ECG systems from emerging countries will help market players overcome this concern.

The ECG systems market remains highly competitive at present, with many companies able to offer devices at similar levels of technological sophistication. Collaboration for R&D as well as other parts of the product lifecycle has thus emerged as a major opportunity for players in the global ECG systems market. Collaboration will help players improve their R&D channels, while M&As will also allow multinational players to expand their geographical reach. Major players in the global ECG systems market include Royal Philips Healthcare, Nihon Kohden Corp., Welch Allyn, GE Healthcare, and Medtronic.

Global ECG Systems Market: Regional Dynamics

The global ECG systems market was dominated by North America in 2015. The high prevalence of lifestyle disorders such as diabetes and obesity is a major factor responsible for the dominance of North America in the global ECG systems market. The increasing aging population, which is more prone to cardiac trouble than younger demographics, is another key factor expected to shape the trajectory of the ECG systems market in the region. The Europe market for ECG systems took up the second-largest share in the global market.

The future of the global ECG systems market, though, is expected to be dominated by Asia Pacific, with the increasing prevalence of cardiac disorders and increasing government support in APAC countries expected to help the regional market post strong figures in the coming years.

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The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, Luxembourg)
  • Eastern Europe (Poland, Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market

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Empty Capsules Market Segment Forecast up to 2023

Global Empty Capsules Market: Overview

 The demand for capsules is growing on account of the mounting consumption of medicines worldwide. This trend augurs well for the global empty capsules market, where growth has thus far been driven by the demand for both nongelatin and hard gelatin capsules. The changing demographics of the world have necessitated the greater production of medicines to treat various kinds of diseases. Capsules, being among the most versatile forms of administering drug doses, are thus expected to be consumed in larger volumes over the next few years.

 The typical capsule is made from gelatin and encloses either a single medicinal ingredient or a combination of the same. Empty capsules are available in numerous sizes depending on the dosage of medicine to be administered. The use of gelatin to make capsules is most widespread because the material renders several advantages, including but not limited to better stability in various temperature ranges, its odorlessness and tastelessness, and softness, which makes it easy to swallow. However, the market also features capsules made of other nongelatin-based materials.

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 The demand for empty capsules is expected to rise substantially in the years ahead thanks largely to the overall growth and expansion of the global pharmaceuticals industry. Moreover, the greater demand for nutraceuticals will also provide the global capsules market an opportunity to expand as several food supplements and functional foods are encapsulated to make them convenient for on-the-go consumption.

 Global Empty Capsules Market: Trends, Drivers, and Restraints

 Because capsules are regarded as a convenient method of consuming health supplements and medication, their demand is likely to grow substantially. Moreover, consumers in developing regions now have higher spending power and thus the ability to allocate more funds toward healthcare and preventative healthcare. Besides the pharmaceuticals and nutraceuticals industries, the demand for encapsulated ingredients is also on the rise in the cosmetics and cosmeceuticals sector. These end-user trends will have a far-reaching influence on the growth of the global empty capsules market.

 Although there is no dearth of revenue-generation opportunities in the global empty capsules market, companies will have to brave headwinds in the form of tightening regulatory guidelines and the need for a high initial investment in R&D and manufacturing facilities. Furthermore, in mass markets such as India, where the majority of vegetarian consumers view animal-derived gelatin in a negative light, companies will face the need to find solutions around the problem by focusing more on nongelatin capsules. Overall, globally, the demand for soft gelatin capsules is showing a clear increase, and players are recommended to explore growth avenues in this space.

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 Global Empty Capsules Market: Region-wise Outlook

 The demand for empty capsules is seen to be highest in regions where the pharmaceuticals sector is well developed. Thus, while the developed countries of the west have been the traditional markets for empty capsules, the growing number of pharmaceutical contract research establishments in Asian countries will lead to an increased demand for empty capsules.

 The North America empty capsules market leads in terms of revenue share and the outlook for the Asia Pacific empty capsules market remains positive. Europe follows North America in terms of revenue in the global empty capsules market. A number of companies in the empty capsules market are increasingly moving eastward, causing a shift in the market’s dynamics.

 Companies that currently rake in the highest revenue in the global empty capsules market are ACG Worldwide, Capsugel, Medi-Caps Ltd, Qualicaps, Inc., CapsCanada Corporation, Bright Pharma Caps, Inc., Suheung Co. Ltd, and Snail Pharma Industry Co. Ltd.

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Immunotoxins Market: Industry Overview and Key Factors

Immunotoxins are proteins that include a toxin along with an antibody or growth factor that binds specifically to target. An immunotoxin consists of a specific cell-targeting constituent, usually a monoclonal antibody (mAb) linked to a cell-killing toxin. Chemical conjugation of antibody to whole protein toxin creates immunotoxins, lacking of its natural binding domain. Immunotoxins are created in Escherichia coli that are distorted with a plasmid encoding the recombinant toxin. Harvesting recombinant protein is the most common method for manufacturing a substance for clinical trial. The insoluble protein is washed thoroughly with detergent to remove solublized, endotoxin, denatured, and condensed in guanidine-dithioerythritol solution. Then the recombinant protein is restored as a denatured protein or also known as renatured protein by rapid intensity into redox buffer containing glutathione and arginine, and the dialyzed renatured protein purified by sizing chromatography and anion exchange.

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Toxins used in immunotoxin structures are derived from fungi, bacteria and plants, while most function by inhibiting protein synthesis. The bacterial toxins that are commonly used in immunotoxins include the toxin from Pseudomonas exotoxin (PE) and Diphtheria toxin (DT). Ribosomes inactivating proteins (RIPs) gelonin, the A chain of ricin (RTA), pokeweed antiviral protein and dodecandron are included in plant toxins that are utilized in immunotoxins. As it is an enzyme, one toxin molecule can work on many substrate molecules, having a lethal effect on the cell. Immunotoxin’s use in haematological malignancies is considered to be very important, which are characterized by a high percentage of malignant cells that express the target antigen in contrast to solid tumours, which are characterized by a mixed cell population, and cells that are often not easily accessible for immunotoxin.

According to a research, cancer was observed as the most frequent cause of death in most of the developed countries. In the U.S., the estimated number of new cancer cases was above 1.5 million in 2010, with a mortality rate accounting for 23% of total deaths. Thus, cancer is observed to be the major application of immunotoxin, to use highly potent agents as a cancer therapy, it is necessary to target the killing agent selectively to the cancer cells and immunotoxin therapy is also considered to be an important and effective molecular cancer treatment strategy. The major driver of immunotoxins market is increasing global prevalence of cancer. For instance, according to World Health Organization (WHO) in 2012, Cancers figure among the leading causes of death worldwide, accounting for 8.2 million deaths while lung, liver, stomach, colorectal and breast cancers cause the most cancer deaths each year. It is also expected that annual cancer cases will rise from 14 million in 2012 to 2022 within the next two decades.

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Major advantages of immunotoxins are minimum toxicity in normal tissues and discerning cytotoxicity towards tumor cells. The immunotoxin’s clinical development in the treatment of solid tumors has been impeded in part, by the initiation of an immune response directed mainly against the toxin moiety, and in part by loss of activity of the fusion protein, e.g. by sterical barrier in the case of large toxin moieties. Strategies to overcome these limitations and develop the clinical performance of immunotoxins may reduce immunogenicity of it by removing the T-cell epitopes and use bispecific or bivalent constructs as next generation molecules.

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Global Home Healthcare Market to Gain Impetus from Rising Base of Geriatric Population

A new study by Transparency Market Research (TMR), titled “Home Health Care Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 – 2024,” states that the increasing base of geriatric population and the rising incidence of chronic diseases are boosting the market significantly.

In addition to this, the emergent technical advancements in the field of home healthcare and the growing demand for highly effective yet cost-efficient healthcare delivery systems are expected to propel this market during the forecast period. However, the rising concerns over patients’ safety, consistent changes in reimbursement policies, and insufficient insurance coverage options are likely to hamper the growth of this market in the coming years, notes the research study.

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The report studies the global home healthcare market on the basis of the product, service, delivery mode, and the region. Based on product, the market has been categorized into mobility care products, testing, monitoring, and screening products, and therapeutic products. Among these, the demand for testing, monitoring, and screening products is rising significantly.

Further, the study has classified the mobility care products segment into cranes, crutches, walkers, mobility scooters, and wheelchairs. The testing, monitoring, and screening products segment has been classified into heart monitoring systems, peak flow meters, blood pressure monitors, pulse oximeters, HIV test kits, and ovulation and pregnancy kits. Oxygen delivery systems, ventilators, nebulizers, wound care products, inhalers, insulin delivery devices, and dialysis devices have been identified as the main therapeutic products available in the home healthcare market.

Based on service, the report has segmented the worldwide home healthcare market into rehabilitation services, infusion therapy services, unskilled care services, respiratory therapy services, pregnancy care services, skilled care services, and palliative care and hospice. The infusion services segment is likely to gain significant impetus from the increasing demand for these services over the forecast period.

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By delivery mode, the market has been categorized into cloud-based home healthcare, web-based home healthcare, and on-premise home healthcare. Among these, the cloud-based segment is projected to dominate the global market over the forecast period.

Region-wise, the report has segmented the global market for home healthcare into North America, Asia Pacific, Europe, and the Rest of the World.

A&D Co. Ltd., Apria Healthcare Group Inc., Almost Family Inc., Abbott Laboratories, Amedisys Inc., Fresenius Se & Co. KGaA, General Electric Co., Kindred Healthcare Inc., Kinnser Software Inc., LHC Group Inc., Linde Group, Mckesson Corp., Omron Corp., Philips Healthcare, and  Roche are some of the key players operating in the home healthcare market, states the research report.